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KMID : 0359020070340020103
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Korean Journal of Gastrointestinal Endoscopy
2007 Volume.34 No. 2 p.103 ~ p.107
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A Case of Diffuse Large B Cell Lymphoma Transformed from a Duodenal Low Grade MALT Lymphoma
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Kim Soon-Joo
Lee Gin-Hyug
Park Sang-Hyun
Shin Hyun-Deok
Jo Chang-Lae
Kim Tae-Hyup
Song Ho-June
Choi Kee-Don
Jung Hwoon-Yong
Kim Jin-Ho
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Abstract
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Duodenal mucosa-associated lymphoid tissue (MALT) lymphoma is a very rare neoplasm. We report here a case of a 67-year-old woman with a diffuse large B cell lymphoma arising in a low grade MALT lymphoma in the duodenal bulb. She was asymptomatic and on a general health evaluation an upper endoscopy showed an extensive erosive lesion on the duodenal bulb. The biopsy specimen showed lymphocyte infiltration with lymphoepithelial lesions suggesting a low grade MALT lymphoma. A second upper endoscopy with biopsy discovered a focal diffuse large B cell lymphoma in the background of a low grade MALT lymphoma. A meticulous staging work-up revealed that the lymphoma was confined to the duodenum and regional lymph nodes. Finally, the patient was diagnosed as having a diffuse large B cell lymphoma transformed from a duodenal low grade MALT lymphoma. The patient was undergoing combination chemotherapy including the use of an anti-CD20 monoclonal antibody.
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KEYWORD
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Lymphoma, Mucosa-associated Lymphoid tissue, Diffuse Large B cell
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